BrewDog will close 10 of its bars this week, including its first ever venue in Aberdeen.
It is understood the closure plans, which are part of a fresh strategy for the brewing firm's hospitality arm, will put close to 100 jobs at risk.
The Scottish craft brewing giant said it has made efforts to preserve the sites but "has simply not been possible to make these bars commercially viable".
The affected bars will shut on July 26 and BrewDog will launch a consultation process lasting at least 14 days.
Aberdeen flagship among closures
The closures are set to include BrewDog's Aberdeen flagship pub on Gallowgate, which was the group's first ever bar site, the company said.
Chief executive James Taylor told staff the closures are part of a refresh of its estate, partly in response to "rising costs, increased regulation, and economic pressures" on the sector.
However, he said the brand still plans to grow its bar business through larger "destination" venues and smaller community bars.
A BrewDog spokesman said the closures reflect "a more focused strategy and a rationalisation of our bar footprint".
"This decision is not simply a response to the challenging UK hospitality market, but a proactive decision to redefine the bar division's focus for long-term and profitable growth - accounting for ongoing industry challenges, including rising costs, increased regulation, and economic pressures."
The company said it expected to redeploy many affected team members across the BrewDog network.
For those leaving the business, BrewDog promised to provide "as much support as possible during this transition".
The closures will affect venues in Aberdeen Gallowgate, Brighton, Camden in London, Dundee, Leeds North Street, Oxford, Sheffield, Shepherds Bush in London, Shoreditch in London, and York.
(PA) Note: This article has been edited with the help of Artificial Intelligence.
